And Jack Wilshere, who joined the Hammers from Arsenal in the summer, is sidelined with an ankle problem.
"He [Hazard] told me after the match against Cardiff he was exhausted so I thought it was better [for him] to rest", Sarri said, having confirmed that David Luiz and Mateo Kovacic have also been kept back in London because of fatigue and injury respectively.
Hazard has made a flying start to the season with five goals in as many Premier League appearances.
On current form, he could easily win the award again this season.
"I am very proud to stay and be a Chelsea player". We have our first one with Chelsea, who are top of the table, which is big motivation.
He said: 'It's impossible to start better than Chelsea have.More news: Former rap mogul ‘Suge’ Knight to serve 28 years in prison
After five games, the Clarets are bottom of the league with a just a single point and their fourth straight loss, a 1-0 defeat at Wolverhampton Wanderers, was a woeful performance that raises real concerns for Sean Dyche's team.
"We must be confident at home".
'We will try to do the same as the last game. "We have to concentrate defensively, but I am confident". So I don't know who will be the striker of the future but I think both because we have to play 60 matches.
The former Dortmund man cut the Toffees' defence open to secure a crucial win, and Manuel Pellegrini will be keen to take that confidence into this weekend.
West Ham are looking to keep successive home clean sheets in this fixture for the first time since August 1969.
Italian Sarri has switched last season's back three to a back four and, on this evidence, he still has a lot of work to do to forge them into a competitive unit.
The Belgian forward has won two Premier League titles, the League Cup, the FA Cup and the Europa League during six seasons at Stamford Bridge.