Two fires there are rapidly expanding towards the coast causing the city of Malibu to evacuate.
Since the fire ignited, at least nine people have been confirmed dead, almost 6,500 homes and 90,000 acres have burned and about 30,000 residents have evacuated, media reports said. Some of the "majestic oaks" the town boasts of on its website still have fires burning in their trunks.
Thousands of people were evacuated from Paradise, home to 26,000 people, including from schools and hospitals.
The Camp Fire ignited Thursday and evolved into the most fierce of the wind-driven fires in what has been one of the worst years for wildfires in California. Evacuation zones were posted on Cal Fire's website.
The official estimate of acreage burned is nearly certainly on the low end, as the fire is spreading at an astonishing 0.32km² per minute.
The blaze also destroyed the home of "Dr". The blaze broke out in the Hill Canyon area and in just 12 minutes jumped the 101 Freeway. Per USA Today, the three fires stretched a combined area of 33,000 acres as of Friday.
"Fire is burning out of control, heading into populated areas of Malibu".
State officials put the total number of people forced from their homes at about 250,000.
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An estimated 75,000 homes were also evacuated along the borders of Ventura and Los Angeles counties, according to AP. "I pray everyone is safe", she wrote. "And the risks are there constantly and we keep that in mind and we try to keep our safety practices at the forefront and bring everyone home safely", Nelson said.
The singer Lady Gaga said she had evacuated her home in Malibu, posting a video on Instagram that showed dark smoke billowing overhead.
Director Guillermo del Toro revealed on Twitter that Bleak House, his museum of horror movie memorabilia was also in the path of the flames.
Some may have lost their lives trying to flee the Camp Fire.
Flames from the unchecked, 20,000-acre (8,100-hectare) Camp Fire were being driven westward by 35-mile-per hour (56 km-per-hour) winds, fire officials said.
The town saw 6,700 homes and businesses ravaged by the fire, one of the most destructive in state history. It's enough to make one wonder how much longer we can keep building in harm's way.
Two firefighters and several residents were injured, and it's not clear if there were any fatalities, Butte County Cal Fire Chief Darren Read told AP.
Mr Murphy said firefighters were able to stop the fire at the edge of the city, where evacuation orders remain in place.
Authorities issued mandatory evacuation orders for more than 50,000 people in the scenic area in the foothills of the Sierra Nevada mountains, including some residents of Chico, population 93,000, near Paradise.