The freaky theory, which has cropped up repeatedly throughout Trump's term in office, suggests that a body double for Melania accompanies the U.S. president at certain events, most recently a visit to survivors of a tornado in Alabama.
"The Fake News photoshopped pictures of Melania, then propelled conspiracy theories that it's actually not her by my side in Alabama and other places", he tweeted, without providing evidence.More news: Greek man who missed Ethiopian Airlines flight shares emotional post
But the US President has now hit back at the rumours - following fresh body double claims circulating earlier this week after the First Lady was pictured with her husband in Georgia, US. "They are only getting more deranged with time!" the president tweeted.
"The Fake News Media has been so unfair, and vicious, to my wife and our great First Lady, Melania", he tweeted at the time. Trump was referring to President John F. Kennedy's wife, Jacqueline Kennedy Onassis, who often was referred to as "Jackie O" after she remarried following Kennedy's assassination.
On Tuesday, Ms Trump issued an angry response through her spokesperson to ABC, after a segment on daytime talk show The View made fun of the ongoing conspiracy. "Sorry", Behar said of one photo.
"People died, people lost family and people are hurting in Alabama", Grisham added in her statement. "I wasn't going to go along with this but that one in that picture doesn't look like her. ..."