Cardinal Timothy Dolan, the archbishop of NY, said he was praying "to ask the intercession of Notre Dame, our Lady, for the Cathedral at the heart of Paris, and of civilization, now in flames!"
On Monday, French President Emmanuel Macron also took to Twitter to express the structure's significance to France and pledge that it would be restored. It is one of the finest examples of French Gothic architecture in existence and 12 million people visit the cathedral every year.
The former United States president called Notre Dame "one of the world's greatest treasures".
A massive fire has engulfed the roof of Notre Dame Cathedral in the heart of Paris, shooting up its long spire and sending thick plumes of smoke high into the blue sky as tourists and Parisians looked on aghast. The French leader also praised the "courage" and "great professionalism" of firefighters who battled the blaze for approximately four hours.
Construction on Notre Dame Cathedral commenced in 1160, though it has been under construction, expansion, and various degrees of restoration ever since.
A centuries-old crown of thorns made from reeds and gold and the tunic worn by Saint Louis, a 13th century king of France, were saved, Notre-Dame's top administrative cleric, Monsignor Patrick Chauvet said.More news: Tiger Woods cops accidental slide tackle after miracle shot at US Masters
"It's a really sad time in Paris", she said.
A firefighter at the scene said all efforts were being directed at saving the northern tower and the artwork at the back of the cathedral. There is now no word on the cause of the fire.
Since then, it has undergone numerous restoration works, and ironically, latest restoration works may result in its final destruction.
"Thinking about Paris", Ament tweeted, with photos of the cathedral.
The Mayor of London called the scenes in Paris "heartbreaking" and said London stood with Paris in sorrow. After emerging to face a throng of reporters, Marcon vowed the cathedral would be rebuilt and announced the launch of an worldwide fundraising drive to begin raising the millions of dollars necessary to restore the building to its former glory.
"I am following minute by minute the fire that is preying on Notre Dame".